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Understanding Drug Use and Addiction DrugFacts National Institute on Drug Abuse NIDA

Nicotine is rapidly absorbed into the bloodstream and stimulates the adrenal glands to release adrenaline (epinephrine), which activates the central nervous system. It also acts on the brain’s reward system to release dopamine—briefly stabilizing mood and providing a short-lived but powerful incentive to repeat the experience. Other chemicals present in tobacco may magnify the effect of tobacco on...

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